UGT1A8
allele nomenclature (view change log)
Allele
naming |
Protein |
Nucleotide
change |
Amino acid
change |
Effect
|
Enzyme activity |
Genbank |
References
|
Notes |
|
In vivo |
In vitro |
||||||||
UGT1A8*1a |
UGT1A8.1 |
|
|
Wild-type |
|
|
|
|
|
UGT1A8*1b |
UGT1A8.1 |
765(A>G) |
T255T |
Silent |
|
|
N/A |
Renamed from *1a |
|
UGT1A8*2 |
UGT1A8.2 |
518(C>G) |
A173G |
|
|
Similar to *1 |
|
||
UGT1A8*3 |
UGT1A8.3 |
830(G>A) |
C277Y |
|
|
Severely reduced |
N/A |
|
N/A : data not available in the manuscript