UGT1A5
allele nomenclature (view change log)
Allele naming |
Protein |
Nucleotide change |
Amino acid change |
Effect |
Enzyme activity |
Genbank |
Reference |
Notes |
|
In vivo |
In vitro |
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UGT1A5*1 |
UGT1A5.1 |
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|
Wild-type |
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|
|
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|
UGT1A5*2 |
UGT1A5.2 |
473(C>G) |
A158G |
|
|
|
Guillemette et al., unpublished data |
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|
UGT1A5*3 |
UGT1A5.3 |
673(C>T) |
H225Y |
|
|
|
Guillemette et al., unpublished data |
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|
UGT1A5*4 |
UGT1A5.4 |
742(C>A)/745(G>C)/776(G>C) |
L248I/V249L/G259A |
|
|
|
Guillemette et al., unpublished data |
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|
UGT1A5*5 |
UGT1A5.5 |
473(C>G)/742(C>A)/745(G>C)/776(G>C) |
A158G/L248I/V249L/G259A |
|
|
|
Guillemette et al., unpublished data |
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|
UGT1A5*6 |
UGT1A5.6 |
673(C>T)/742(C>A)/745(G>C)/776(G>C) |
H225Y/L248I/V249L/G259A |
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|
|
Guillemette et al., unpublished data |
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|
UGT1A5*7 |
UGT1A5.7 |
473(C>G)/673(C>T)/742(C>A)/745(G>C)/776(G>C) |
A158G/H225Y/L248I/V249L/G259A |
|
|
|
Guillemette et al., unpublished data |
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